Genome Biology aims to provide the best possible service to authors and readers of primary research articles. The refereed research section publishes peer-reviewed research in all areas of molecular, cellular, organismal and population biology that are informed by genomics. All research articles are made available free to individuals through the web, and there are no restrictions on article length or on the types of information that can be included. The publication schedule is very fast, using electronic systems for article delivery, proofing and peer-review. For more details about how refereed research is published in Genome Biology and for instructions for authors, see 'about refereed research'.

Research    

(6 May 2008)

A 10X draft sequence of Podospora anserina genome shows highly dynamic evolution since its divergence from Neurospora crassa.

Method    

(7 April 2008)

ModuleMiner detects cis-regulatory modules in a set of co-expressed genes in tissue-specific microarray clusters and in embryonic development datasets.

Research    

(22 April 2008)

Comparative genome hybridization in 38 widely used laboratory strains of the social amoeba Dictyostelium discoideum detects previously unreported duplications and deletions in the Dictyostelium genome and highlights genetic variability between strains.

Method    

(8 April 2008)

So-called Evolutionary potentials for protein structure prediction are derived using a single experimental protein structure and all three-dimensional models of its homologous sequences.

Research    

(17 April 2008)

The neuronally expressed transcription factor gene ewg is shown to be a major target of the RNA-binding protein ELAV. EWG restricts synaptic growth at neuromuscular junctionsby integrating multiple signal pathways.

Method    

(3 April 2008)

A new system based on non-conventional secretion of the luciferase from Gaussia princeps (GLUC) can be used to detect intracellular proteolysis in vivo.

Research    

(10 April 2008)

Transcript and metabolite abundance changes were analyzed in evolved and ancestor strains of Escherichia coli in three different evolutionary conditions

Research    

(9 April 2008)

A comparative genomic and proteomic study of halophilic and non-halophilic prokaryotes identifies specific genomic and proteomic features typical of halophilic species that are independent from genomic GC-content and taxonomic position.