Genome Biology aims to provide review material that readers need in order to assess and evaluate progress in genomic and post-genomic research. Reviews include systematic and substantial coverage of mature subjects, rapid coverage of fast-moving areas, evaluations of progress in specified areas, and critical assessments of emerging technologies. Reviews are usually commissioned, with the editors aiming to ensure coverage of all relevant areas of biology and genomics but suggestions of reviews are welcome.

Minireview   

(1 September 2008)

Massively parallel sequencing has been harnessed to map DNA methylation patterns in the mouse genome.

Review   

(28 August 2008)

The phytochrome protein superfamily reveals a diversity of mechanisms of action.

Protein family review   

(29 July 2008)

Tektins are insoluble a-helical proteins essential for the construction of cilia and flagella and are found throughout the eukaryotes apart from higher plants.

Review   

(29 July 2008)

A review of the mechanisms that control organ size in plants.

Minireview   

(28 July 2008)

DNA damage response signaling has been achieved experimentally in the absence of double-strand DNA breaks.

Review   

(24 June 2008)

A review of the evolution of microbial pathogenicity in the context of the 'symbiome' of microbes and their multicellular hosts.

Minireview   

(17 June 2008)

A new polyomavirus has been discovered in Merkel cell carcinomas, but does it contribute to carcinogenesis?

Protein family review   

(17 June 2008)

An overview of the AID/APOBEC family of cytidine deaminases, enzymes that can mutate RNA and DNA.