Genome Biology aims to provide review material that readers need in order to assess and evaluate progress in genomic and post-genomic research. Reviews include systematic and substantial coverage of mature subjects, rapid coverage of fast-moving areas, evaluations of progress in specified areas, and critical assessments of emerging technologies. Reviews are usually commissioned, with the editors aiming to ensure coverage of all relevant areas of biology and genomics but suggestions of reviews are welcome.

Review   

(2 May 2008)

Promoter-proximal polymerase II stalling prepares genes for prompt expression when signals are received.

Minireview   

(30 April 2008)

TOPLESS acts as a corepressor of auxin-mediated gene expresssion in plant development.

Review   

(30 April 2008)

The AAA+ superfamily is a large superfamily of ATPases that are characterized by a conserved catalytic module, the AAA+ module. Members are involved in an astonishing range of different cellular processes.

Minireview   

(25 April 2008)

The mammalian NOD-like receptor NLRX1 appears to have a role as a regulator of antiviral response pathways.

Review   

(24 April 2008)

New techniques are enabling the identification of genetic variants underlying complex diseases and phenotypic traits.

Minireview   

(24 April 2008)

Inhibition of the cellular RNA surveillance system in Arabidopsis reveals a normally hidden transcriptome of small noncoding RNAs.

Review   

(10 March 2008)

A variety of innate immune system receptors recognize and respond to the nucleic acids of invading pathogens.

Minireview   

(31 March 2008)

Drosophila larvae with a single sense organ locate a source of odor as well as larvae with two.