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10th Anniversary Collection

Collection published: 5 May 2010

Since its launch in 2000, Genome Biology has become a premier journal for genomics research. We are celebrating our success over the last ten years with a series of exciting reviews and special content that mark key developments in the genomics field over this period.

		Review GWASs and the age of human as the model organism for autoimmune genetic research Robert Plenge Genome Biology 2010, 11:212 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Humans should perhaps be the model organism for autoimmune disease studies, considering the success of GWAS studies uncovering risk alleles.
		Review Cancer genomics identifies determinants of tumor biology Elaine R Mardis Genome Biology 2010, 11:211 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Whole-genome analysis of human tumors has identified some unsuspected tumor-associated genes
		Review Direct sequencing of the human microbiome readily reveals community differences Justin Kuczynski, Elizabeth K Costello, Diana R Nemergut, Jesse Zaneveld, Christian L Lauber, Dan Knights, Omry Koren, Noah Fierer, Scott T Kelley, Ruth E Ley, Jeffrey I Gordon, Rob Knight Genome Biology 2010, 11:210 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Future sequencing of the human microbiota will require greater breadth rather than depth.
		Review The origin and early evolution of eukaryotes in the light of phylogenomics Eugene V Koonin Genome Biology 2010, 11:209 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Comparative genomics and new phylogenies of eukaryote groups suggest a scenario in which the mitochondrial endosymbiosis triggered the origin of eukaryotes.
		Review The next frontier of systems biology: higher-order and interspecies interactions Michael A Fischbach, Nevan J Krogan Genome Biology 2010, 11:208 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Systems biology is set to go beyond single species to the study of interspecies interactions.
		Review The case for cloud computing in genome informatics Lincoln D Stein Genome Biology 2010, 11:207 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 3 comments \| Editor’s summary With DNA sequencing now getting cheaper more quickly than data storage, the time may have come to use cloud computing for genome informatics.
		Review Between a chicken and a grape: estimating the number of human genes Mihaela Pertea, Steven L Salzberg Genome Biology 2010, 11:206 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The number of genes in the human genome is still an estimate.
		Comment And they said it wouldn't last... Gregory A Petsko Genome Biology 2010, 11:121 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary In the 10 years that Genome Biology has been published the scientific changes have been amazing, as have the changes in the culture of science.
		Editorial A decade and genome of change Clare Garvey Genome Biology 2010, 11:120 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Innovations in genomic technologies have generated huge advances in biomedical research over the last decade.

		Review GWASs and the age of human as the model organism for autoimmune genetic research Robert Plenge Genome Biology 2010, 11:212 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Humans should perhaps be the model organism for autoimmune disease studies, considering the success of GWAS studies uncovering risk alleles.
		Review Cancer genomics identifies determinants of tumor biology Elaine R Mardis Genome Biology 2010, 11:211 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Whole-genome analysis of human tumors has identified some unsuspected tumor-associated genes
		Review Direct sequencing of the human microbiome readily reveals community differences Justin Kuczynski, Elizabeth K Costello, Diana R Nemergut, Jesse Zaneveld, Christian L Lauber, Dan Knights, Omry Koren, Noah Fierer, Scott T Kelley, Ruth E Ley, Jeffrey I Gordon, Rob Knight Genome Biology 2010, 11:210 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Future sequencing of the human microbiota will require greater breadth rather than depth.
		Review The origin and early evolution of eukaryotes in the light of phylogenomics Eugene V Koonin Genome Biology 2010, 11:209 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Comparative genomics and new phylogenies of eukaryote groups suggest a scenario in which the mitochondrial endosymbiosis triggered the origin of eukaryotes.
		Review The next frontier of systems biology: higher-order and interspecies interactions Michael A Fischbach, Nevan J Krogan Genome Biology 2010, 11:208 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Systems biology is set to go beyond single species to the study of interspecies interactions.
		Review The case for cloud computing in genome informatics Lincoln D Stein Genome Biology 2010, 11:207 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 3 comments \| Editor’s summary With DNA sequencing now getting cheaper more quickly than data storage, the time may have come to use cloud computing for genome informatics.
		Review Between a chicken and a grape: estimating the number of human genes Mihaela Pertea, Steven L Salzberg Genome Biology 2010, 11:206 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The number of genes in the human genome is still an estimate.
		Comment And they said it wouldn't last... Gregory A Petsko Genome Biology 2010, 11:121 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary In the 10 years that Genome Biology has been published the scientific changes have been amazing, as have the changes in the culture of science.
		Editorial A decade and genome of change Clare Garvey Genome Biology 2010, 11:120 (5 May 2010) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Innovations in genomic technologies have generated huge advances in biomedical research over the last decade.