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Genome Biology publishes and distributes software, and may provide links to software available elsewhere. Descriptions of software may be subject to peer review as for primary research articles. All software articles are made available free to individuals through the web, and there are no restrictions on article length or on the types of information that can be included. The publication schedule is very fast, using electronic systems for article delivery, proofing and peer-review. For more details about how software is published in Genome Biology and for instructions for authors, see 'about refereed research'.
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Software

Genome assembly forensics: finding the elusive mis-assembly

Software    
Adam M Phillippy, Michael C Schatz, Mihai Pop
(14 March 2008)

A collection of software tools is combined for the first time in an automated pipeline for detecting large-scale genome assembly errors and for validating genome assemblies.

[Abstract] [Provisional PDF]

Ancora: a web resource for exploring highly conserved noncoding elements and their association with developmental regulatory genes

Software    
Pär G Engström, David Fredman, Boris Lenhard
(15 February 2008)

Ancora is a web resource that provides data and tools for exploring genomic organization of highly conserved noncoding elements for multiple genomes.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

MetaReg: a platform for modeling, analysis and visualization of biological systems using large-scale experimental data

Software    
Igor Ulitsky, Irit Gat-Viks, Ron Shamir
(2 January 2008)

A new computational tool is presented that allows the integration of high-throughput experimental results with the probabilistic modeling of previously obtained information about cellular systems. The tool (MetaReg) is demonstrated on the leucine biosynthesis system in S.cerevisiae.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites

Software    
Florian Gnad, Shubin Ren, Juergen Cox, Jesper V Olsen, Boris Macek, Mario Oroshi, Matthias Mann
(26 November 2007)

PHOSIDA, a phosphorylation site database, integrates thousands of phosphosites identified by proteomics in various species.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation

Software    
Elodie Portales-Casamar, Stefan Kirov, Jonathan Lim, Stuart Lithwick, Magdalena I Swanson, Amy Ticoll, Jay Snoddy, Wyeth W Wasserman
(28 September 2007)

PAZAR is an open-access and open-source database of transcription factor and regulatory sequence annotation with associated web interface and programming tools for data submission and extraction.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

RASTA-Bacteria: a web-based tool for identifying toxin-antitoxin loci in prokaryotes

Software    
Emeric W Sevin, Frédérique Barloy-Hubler
(1 August 2007)

RASTA-Bacteria is an automated method that allows quick and reliable identification of toxin/antitoxin loci in sequenced prokaryotic genomes, whether they are annotated Open Reading Frames or not.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

PyCogent: a toolkit for making sense from sequence

Software    
Rob Knight, Peter Maxwell, Amanda Birmingham, Jason Carnes, J Gregory Caporaso, Brett C Easton, Michael Eaton, Micah Hamady, Helen Lindsay, Zongzhi Liu, Catherine Lozupone, Daniel McDonald, Michael Robeson, Raymond Sammut, Sandra Smit, Matthew J Wakefield, Jeremy Widmann, Shandy Wikman, Stephanie Wilson, Hua Ying, Gavin A Huttley
(21 August 2007)

The COmparative GENomic Toolkit, a framework for probabilistic analyses of biological sequences, devising workflows and generating publication quality graphics, has been implemented in Python.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Strategy for encoding and comparison of gene expression signatures

Software    
Yajun Yi, Chun Li, Clay Miller, Alfred L George Jr
(5 July 2007)

EXALT (EXpression signature AnaLysis Tool) enables comparisons of microarray data across experimental platforms and different laboratories.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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