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Genome Biology publishes and distributes software, and may provide links to software available elsewhere. Descriptions of software may be subject to peer review as for primary research articles. All software articles are made available free to individuals through the web, and there are no restrictions on article length or on the types of information that can be included. The publication schedule is very fast, using electronic systems for article delivery, proofing and peer-review. For more details about how software is published in Genome Biology and for instructions for authors, see 'about refereed research'.
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Software

The Cell Cycle Ontology: An application ontology for the representation and integrated analysis of the cell cycle process

Software    
Erick Antezana, Mikel Egana, Ward Blonde, Aitzol Illarramendi, Inaki Bilbao, Bernard De Baets, Robert Stevens, Vladimir Mironov, Martin Kuiper
(29 May 2009)

A software resource for the analysis of cell cycle related molecular networks.

[Abstract] [Provisional PDF]

MotifAdjuster: a tool for computational reassessment of transcription factor binding site annotations

Software    
Jens Keilwagen, Jan Baumbach, Thomas A Kohl, Ivo Grosse
(1 May 2009)

MotifAdjuster helps to detect errors in binding site annotations.

[Abstract] [Provisional PDF] [PubMed] [Related articles]

Chromatin conformation signatures of cellular differentiation

Software    
James Fraser, Mathieu Rousseau, Solomon Shenker, Maria A Ferraiuolo, Yoshihide Hayashizaki, Mathieu Blanchette, Josée Dostie
(19 April 2009)

A suite of computer programs to identify genome-wide chromatin conformation signatures with 5C technology is reported.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

FANTOM4 EdgeExpressDB: an integrated database of promoters, genes, microRNAs, expression dynamics and regulatory interactions

Software    
Jessica Severin, Andrew M Waterhouse, Hideya Kawaji, Timo Lassmann, Erik van Nimwegen, Piotr J Balwierz, Michiel JL de Hoon, David A Hume, Piero Carninci, Yoshihide Hayashizaki, Harukazu Suzuki, Carsten O Daub, Alistair RR Forrest
(19 April 2009)

EdgeExpressDB is a novel database and set of interfaces for interpreting biological networks and comparing large high-throughput expression datasets.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

TFCat: the curated catalog of mouse and human transcription factors

Software    
Debra L Fulton, Saravanan Sundararajan, Gwenael Badis, Timothy R Hughes, Wyeth W Wasserman, Jared C Roach, Rob Sladek
(12 March 2009)

TFCat is a catalog of mouse and human transcription factors based on a reliable core collection of annotations obtained by expert review of the scientific literature

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Software    
Ben Langmead, Cole Trapnell, Mihai Pop, Steven L Salzberg
(4 March 2009)

Bowtie: a new ultrafast memory-efficient tool for the alignment of short DNA sequence reads to large genomes.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

PEMer: a computational framework with simulation-based error models for inferring genomic structural variants from massive paired-end sequencing data

Software    
Jan O Korbel, Alexej Abyzov, Xinmeng Jasmine Mu, Nicholas Carriero, Philip Cayting, Zhengdong Zhang, Michael Snyder, Mark B Gerstein
(23 February 2009)

Paired-End Mapper (PEMer) enables mapping of genomic structural variants at considerably enhanced sensitivity, specificity and resolution over previous approaches.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

EpiGRAPH: user-friendly software for statistical analysis and prediction of (epi)genomic data

Software    
Christoph Bock, Konstantin Halachev, Joachim Büch, Thomas Lengauer
(10 February 2009)

EpiGRAPH is a genome-scale data-mining software tool that enables users to identify epigenetic and gene regulatory features in large datasets of genomic regions.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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