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Genome Biology publishes and distributes software, and may provide links to software available elsewhere. Descriptions of software may be subject to peer review as for primary research articles. All software articles are made available free to individuals through the web, and there are no restrictions on article length or on the types of information that can be included. The publication schedule is very fast, using electronic systems for article delivery, proofing and peer-review. For more details about how software is published in Genome Biology and for instructions for authors, see 'about refereed research'.
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Software

PhenomiR: a knowledgebase for microRNA expression in diseases and biological processes

Software    
Andreas Ruepp, Andreas Kowarsch, Daniel Schmidl, Felix Bruggenthin, Barbara Brauner, Irmtraud Dunger, Gisela Fobo, Goar Frishman, Corinna Montrone, Fabian J Theis
(20 January 2010)

PhenomiR is a comprehensive database of 542 studies reporting deregulation of miRNAs allowing large-scale statistical analysis of miRNA expression changes.

[Abstract] [Provisional PDF]

Mining for coexpression across hundreds of datasets using novel rank aggregation and visualisation methods

Software    
Priit Adler, Raivo Kolde, Meelis Kull, Aleksandr Tkachenko, Hedi Peterson, Juri Reimand, Jaak Vilo
(4 December 2009)

The MEM web resource allows users to search for co-expressed genes across all microarray datasets in the ArrayExpress database.

[Abstract] [Provisional PDF] [PubMed] [Related articles]

Searching for SNPs with cloud computing

Software    
Ben Langmead, Michael C Schatz, Jimmy Lin, Mihai Pop, Steven L Salzberg
(20 November 2009)

Novel software utilizing cloud computing technology to cost-effectively align and map SNPs from a human genome in three.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources

Software    
Chunlei Wu, Camilo Orozco, Jason Boyer, Marc Leglise, James Goodale, Serge Batalov, Christopher L Hodge, James Haase, Jeff Janes, Jon W Huss III, Andrew I Su
(17 November 2009)

BioGPS is a community based customisable gene annotation portal bringing together gene annotation resources on to a single platform.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

A compiled and systematic reference map of nucleosome positions across the Saccharomyces cerevisiae genome

Software    
Cizhong Jiang, B Franklin Pugh
(8 October 2009)

Different genome-wide reference maps of Saccharomyces cerevisiae nucleosome positions are compiled and can be visualized on a browser.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

MethMarker: user-friendly design and optimization of gene-specific DNA methylation assays

Software    
Peter Schüffler, Thomas Mikeska, Andreas Waha, Thomas Lengauer, Christoph Bock
(5 October 2009)

A software workflow to translate known differentially methylated regions into clinical biomarkers

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Simultaneous alignment of short reads against multiple genomes

Software    
Korbinian Schneeberger, Jörg Hagmann, Stephan Ossowski, Norman Warthmann, Sandra Gesing, Oliver Kohlbacher, Detlef Weigel
(17 September 2009)

New software for the alignment of short-read sequence data to multiple genomes allows identification of polymorphisms that cannot be identified by alignment to a single reference genome.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Synorth: exploring the evolution of synteny and long-range regulatory interactions in vertebrate genomes

Software    
Xianjun Dong, David Fredman, Boris Lenhard
(21 August 2009)

Synorth is a web resource for exploring and categorizing the syntenic relationships in gene regulatory blocks across multiple genomes.

[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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