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Genome Biology publishes selected collections of research articles, conference proceedings, reviews and reports as supplements, which are free to access online. All articles published in supplements are subject to peer review; meeting abstracts undergo review and selection by the conference. Find out more about publishing a supplement with BioMed Central.

Volume 12 Supplement 1

Beyond the Genome 2011

Meeting abstracts

Beyond the Genome 2011

Washington, DC, USA

19-22 September 2011

Additional Information | Conference website

Invited speaker presentation   Open Access

Analysis of 2,440 human exomes highlights the evolution and functional impact of rare coding variation

Joshua Akey Genome Biology 2011, 12(Suppl 1):I1 (19 September 2011)

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Invited speaker presentation   Open Access

Abstract not submitted for online publication

Genome Biology 2011, 12(Suppl 1):I2 (19 September 2011)

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Invited speaker presentation   Open Access

Are clinical genomes already becoming semi-routine for patient care?

Mark Boguski Genome Biology 2011, 12(Suppl 1):I3 (19 September 2011)

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Invited speaker presentation   Open Access

Interrogating the architecture of cancer genomes

Peter Campbell Genome Biology 2011, 12(Suppl 1):I4 (19 September 2011)

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Invited speaker presentation   Open Access

Genome-forward oncology: how do we get there?

Matthew Ellis Genome Biology 2011, 12(Suppl 1):I5 (19 September 2011)

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Invited speaker presentation   Open Access

Abstract not submitted for online publication

Genome Biology 2011, 12(Suppl 1):I6 (19 September 2011)

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Invited speaker presentation   Open Access

Microbial reference genomes for human metagenomics

Sarah K Highlander Genome Biology 2011, 12(Suppl 1):I7 (19 September 2011)

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Invited speaker presentation   Open Access

Abstract not submitted for online publication

Genome Biology 2011, 12(Suppl 1):I8 (19 September 2011)

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Invited speaker presentation   Open Access

Next-generation clinical sequencing in a children’s hospital

Stephen Kingsmore Genome Biology 2011, 12(Suppl 1):I9 (19 September 2011)

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Invited speaker presentation   Open Access

A glimpse at tumor genome evolution

Elaine R Mardis Genome Biology 2011, 12(Suppl 1):I10 (19 September 2011)

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Invited speaker presentation   Open Access

Abstract not submitted for online publication

Genome Biology 2011, 12(Suppl 1):I11 (19 September 2011)

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Invited speaker presentation   Open Access

Comparative genomic analysis of mouse and human mammary tumors

Charles M Perou Genome Biology 2011, 12(Suppl 1):I12 (19 September 2011)

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Invited speaker presentation   Open Access

Reconstructing microbial communities

Mihai Pop Genome Biology 2011, 12(Suppl 1):I13 (19 September 2011)

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Invited speaker presentation   Open Access

Next-generation human genetics

Jay Shendure Genome Biology 2011, 12(Suppl 1):I14 (19 September 2011)

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Invited speaker presentation   Open Access

Metatranscriptomics of the human gut microbiome

Thomas Sichertz Pontén Genome Biology 2011, 12(Suppl 1):I15 (19 September 2011)

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Invited speaker presentation   Open Access

De novo mutations in mental retardation

Joris A Veltman Genome Biology 2011, 12(Suppl 1):I16 (19 September 2011)

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Invited speaker presentation   Open Access

Comparative analysis of the vaginal microbiome in health and disease

Bryan A White, Andres M Gomez, Mengfei Ho, Margret Berg Miller, Susan M Thomas, Carl J Yeoman, Suleyman Yildirim, Douglas J Creedon, Tony L Goldberg, Steven R Leigh, Karen E Nelson, Rebecca M Stumpf, Brenda A Wilson Genome Biology 2011, 12(Suppl 1):I17 (19 September 2011)

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Invited speaker presentation   Open Access

The Joint Center for Structural Genomics: exploration of the human gut microbiome

Ian Wilson Genome Biology 2011, 12(Suppl 1):I18 (19 September 2011)

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Poster presentation   Open Access

RNA-Seq methods for imperfect samples: development, evaluation and applications

Xian Adiconis, Lin Fan, David DeLuca, Andrey Sivachenko, Nathalie Pochet, Aaron Berlin, Sarah Young, Gad Getz, Aviv Regev, Chad Nusbaum, Andreas Gnirke, Joshua Z Levin Genome Biology 2011, 12(Suppl 1):P1 (19 September 2011)

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Poster presentation   Open Access

Viral diversity in children with diarrhea in Gambia

Irina Astrovskaya, Bo Liu, Mihai Pop Genome Biology 2011, 12(Suppl 1):P2 (19 September 2011)

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Poster presentation   Open Access

COSMIC: the catalogue of somatic mutations in cancer

Nidhi Bindal, Simon A Forbes, David Beare, Prasad Gunasekaran, Kenric Leung, Chai Kok, Mingming Jia, Sally Bamford, Charlotte Cole, Sari Ward, Jon Teague, Michael R Stratton, Peter Campbell, Andrew P Futreal Genome Biology 2011, 12(Suppl 1):P3 (19 September 2011)

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Poster presentation   Open Access

A novel functional variant in 8q24 is associated with regulation of prostate stem cell antigen (PSCA) gene expression and bladder cancer risk

Yi-Ping Fu, Indu Kohaar, Adam Mumy, Wei Tang, Brian Muchmore, Patricia Porter-Gill, Luyang Liu, Jonine Figueroa, Montserrat Garcia-Closas, Dalsu Baris, Mark Purdue, Michael Thun, Demetrius Albanes, Nuria Malats, Francisco X Real, Manolis Kogevinas, Alison Johnson, Molly Schwenn, Stephen Chanock, Nathaniel Rothman, Debra Silverman, Ludmila Prokunina-Olsson Genome Biology 2011, 12(Suppl 1):P4 (19 September 2011)

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Poster presentation   Open Access

Evaluating short-read sequence data from the highly redundant, novel transcriptome of Polarella glacialis

Theodore R Gibbons, Gregory T Concepcion, Tsvetan R Bachvaroff, Charles F Delwiche Genome Biology 2011, 12(Suppl 1):P5 (19 September 2011)

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Poster presentation   Open Access

A cost-effective and universal strategy for complete prokaryotic genome sequencing proposed by computer simulation

Jingwei Jiang, Jun Li, Frederick C Leung Genome Biology 2011, 12(Suppl 1):P6 (19 September 2011)

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Poster presentation   Open Access

Functional exploration of CCNE1 splicing forms as a possible link to bladder cancer susceptibility

Indu Kohaar, Alexandra Scott-Johnson, Yi-Ping Fu, Patricia Porter-Gill, Ludmila Prokunina-Olsson Genome Biology 2011, 12(Suppl 1):P7 (19 September 2011)

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Poster presentation   Open Access

ScaffViz: visualizing metagenome assemblies

Sergey Koren, Todd Treangen, Mihai Pop Genome Biology 2011, 12(Suppl 1):P8 (19 September 2011)

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Poster presentation   Open Access

Systems biology of bacteriophage proteins and new dimensions of the virus world discovered through metagenomics

David M Kristensen, Arcady R Mushegian, Eugene V Koonin Genome Biology 2011, 12(Suppl 1):P9 (19 September 2011)

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Poster presentation   Open Access

Genetic basis of common human disease: insight into the role of nonsynonymous SNPs from genome-wide association studies

Lipika R Pal, John Moult Genome Biology 2011, 12(Suppl 1):P10 (19 September 2011)

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Poster presentation   Open Access

Accurate and fast estimation of taxonomic profiles from metagenomic shotgun sequences

Bo Liu, Theodore Gibbons, Mohammad Ghodsi, Todd Treangen, Mihai Pop Genome Biology 2011, 12(Suppl 1):P11 (19 September 2011)

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Poster presentation   Open Access

Abstract not submitted for online publication

Genome Biology 2011, 12(Suppl 1):P12 (19 September 2011)

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Poster presentation   Open Access

Massively parallel sequencing identifies a previously unrecognized X-linked disorder resulting in lethality in male infants owing to amino-terminal acetyltransferase deficiency

Alan F Rope, Kai Wang, Rune Evjenth, Jinchuan Xing, Jennifer J Johnston, Jeffrey J Swensen, W Johnson, Barry Moore, Chad D Huff, Lynne M Bird, John C Carey, John M Opitz, Cathy A Stevens, Christa Schank, Heidi Fain, Reid Robison, Brian Dalley, Steven Chin, Sarah T South, Theodore J Pysher, Lynn B Jorde, Hakon Hakonarson, Johan R Lillehaug, Leslie G Biesecker, Mark Yandell, Thomas Arnesen, Gholson J Lyon Genome Biology 2011, 12(Suppl 1):P13 (19 September 2011)

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Poster presentation   Open Access

Abstract not submitted for online publication

Genome Biology 2011, 12(Suppl 1):P14 (19 September 2011)

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Poster presentation   Open Access

Prostate stem cell antigen (PSCA) and risk of bladder cancer: linking genotypes to functional mechanisms

Adam Mumy, Indu Kohaar, Patricia Porter-Gill, Wei Tang, Yi-Ping Fu, Ludmila Prokunina-Olsson Genome Biology 2011, 12(Suppl 1):P15 (19 September 2011)

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Poster presentation   Open Access

Metabolic pathways are affected differently in Saccharomyces cerevisiae thiol peroxidase mutants during redox stress with hydrogen peroxide

Amy L Olex, Brian M Westwood, Leslie B Poole, Jacquelyn S Fetrow Genome Biology 2011, 12(Suppl 1):P16 (19 September 2011)

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Poster presentation   Open Access

Metastats: an improved statistical method for analysis of metagenomic data

Joseph N Paulson, Mihai Pop, Hector Bravo Genome Biology 2011, 12(Suppl 1):P17 (19 September 2011)

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Poster presentation   Open Access

Detection of bladder, breast and prostate cancer using serum and tissue miRNA profiling

Patricia Porter-Gill, Yi-Ping Fu, Alpana Kaushiva, Douglas Price, William Dahut, William Figg, Ludmila Prokunina-Olsson Genome Biology 2011, 12(Suppl 1):P18 (19 September 2011)

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Poster presentation   Open Access

An unusual suspect: an uncommon human-specific synonymous coding variant within the UGT1A6 gene explains a GWAS signal and protects against bladder cancer

Wei Tang, Yi-Ping Fu, Jonine D Figueroa, Núria Malats, Montserrat Garcia-Closas, Nilanjan Chatterjee, Manolis Kogevinas, Dalsu Baris, Michael Thun, Jennifer L Hall, Immaculata De Vivo, Demetrius Albanes, Patricia Porter-Gill, Mark P Purdue, Laurie Burdett, Luyang Liu, Amy Hutchinson, Timothy Myers, Adonina Tardón, Consol Serra, Alfredo Carrato, Reina Garcia-Closas, Josep Lloreta, Alison Johnson, Molly Schwenn, Margaret R Karagas, Alan Schned, Amanda Black, Eric J Jacobs, W Diver, Susan M Gapstur, Jarmo Virtamo, David J Hunter, Joseph F Fraumeni, Stephen J Chanock, Debra T Silverman, Nathaniel Rothman, Ludmila Prokunina-Olsson et al. Genome Biology 2011, 12(Suppl 1):P19 (19 September 2011)

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Poster presentation   Open Access

A comprehensive census of horizontal gene transfers from prokaryotes to unikonts

Pere Puigbò, Sergei Mekhedov, Yuri I Wolf, Eugene V Koonin Genome Biology 2011, 12(Suppl 1):P20 (19 September 2011)

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Poster presentation   Open Access

A genetic survival network for glioblastoma multiforme

Andy Lin, Desmond J Smith Genome Biology 2011, 12(Suppl 1):P21 (19 September 2011)

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Poster presentation   Open Access

Building a protein interaction (PIN) database for autism candidate genes

Catherine Swanwick, Sharmila Banerjee-Basu Genome Biology 2011, 12(Suppl 1):P22 (19 September 2011)

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Poster presentation   Open Access

Whole transcriptome sequencing of normal and tumor bladder tissue samples

Wei Tang, Ludmila Prokunina-Olsson Genome Biology 2011, 12(Suppl 1):P23 (19 September 2011)

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Poster presentation   Open Access

Identification of functional genetic variants associated with prostate cancer through analysis of genome-wide genetic and epigenetic datasets

McAnthony Tarway, Wei Tang, Ludmila Prokunina-Olsson Genome Biology 2011, 12(Suppl 1):P24 (19 September 2011)

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Poster presentation   Open Access

MetAMOS: a metagenomic assembly and analysis pipeline for AMOS

Todd J Treangen, Sergey Koren, Irina Astrovskaya, Dan Sommer, Bo Liu, Mihai Pop Genome Biology 2011, 12(Suppl 1):P25 (19 September 2011)

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Poster presentation   Open Access

The mutation spectrum in Indian patients with Gaucher disease

Vartika Bisariya, Pramod K Mistry, Jun Liu, Madhumita Chaudhari, Neerja Gupta, Madhulika Kabra Genome Biology 2011, 12(Suppl 1):P26 (19 September 2011)

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Poster presentation   Open Access

Boundary distinction interpretation of microarray data via discrete correlate summation

Brian M Westwood, Amy L Olex, James L Norris, Leslie B Poole, Jacquelyn S Fetrow Genome Biology 2011, 12(Suppl 1):P27 (19 September 2011)

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Poster presentation   Open Access

A computational approach to identify transposable element insertions in cancer cells

Israel T Silva, Daniel G Pinheiro, Wilson A Silva Genome Biology 2011, 12(Suppl 1):P28 (19 September 2011)

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Poster presentation   Open Access

Joint analysis of genome-wide genetic variants associated with gene expression and disease susceptibility

Chen-Hsin Yu, John Moult Genome Biology 2011, 12(Suppl 1):P29 (19 September 2011)

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Poster presentation   Open Access

Phylogenomics of prokaryotic ribosomal proteins

Natalya Yutin, Kira S Makarova, Yuri I Wolf, Eugene V Koonin Genome Biology 2011, 12(Suppl 1):P30 (19 September 2011)

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Poster presentation   Open Access

Genomes in a bottle: creating standard reference materials for genomic variation - why, what and how?

Justin M Zook, Marc Salit Genome Biology 2011, 12(Suppl 1):P31 (19 September 2011)

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Poster presentation   Open Access

Deciphering the reproductive protein-protein interaction network in Anopheles gambiae with Drosophila melanogaster as a framework

Daniel Achinko, Paul Mireji, Flaminia Catteruccia, Dan Masig Genome Biology 2011, 12(Suppl 1):P32 (19 September 2011)

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Poster presentation   Open Access

InSilico DB: an online platform to collaboratively structure and export publicly available datasets from the Gene Expression Omnibus database

A Coletta, C Molter, R Duqué, D Steenhoff, J Taminau, V de Schaetzen, C Lazar, S Meganck, A Nowé, H Bersini, D Weiss Genome Biology 2011, 12(Suppl 1):P33 (19 September 2011)

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Poster presentation   Open Access

Introducing the non-B DNA Motif Search Tool (nBMST)

Regina Z Cer, Kevin H Bruce, Duncan E Donohue, Alpay N Temiz, Albino Bacolla, Uma S Mudunuri, Ming Yi, Natalia Volfovsky, Brian T Luke, Jack R Collins, Robert M Stephens Genome Biology 2011, 12(Suppl 1):P34 (19 September 2011)

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Poster presentation   Open Access

Integrating GWAS with gene expression data to dissect the genetic architecture of triple-negative breast cancer

Chindo Hicks, Ranjit Kumar, Antonio Pannuti, Lucio Miele Genome Biology 2011, 12(Suppl 1):P35 (19 September 2011)

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Poster presentation   Open Access

Abstract not submitted for online publication

Genome Biology 2011, 12(Suppl 1):P36 (19 September 2011)

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Poster presentation   Open Access

An amalgamated risk estimation model (REM) and assay integration into future REMs

Peter Cartwright, Erica Ramos, India Bradley, Eric Hanson Genome Biology 2011, 12(Suppl 1):P37 (19 September 2011)

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Poster presentation   Open Access

G-CODE: enabling systems medicine through innovative informatics

Subha Madhavan, Yuriy Gusev, Michael A Harris, David M Tanenbaum, Robinder Gauba, Krithika Bhuvaneshwar, Andrew Shinohara, Kevin Rosso, Lavinia A Carabet, Lei Song, Rebecca B Riggins, Sivanesan Dakshanamurthy, Yue Wang, Stephen W Byers, Robert Clarke, Louis M Weiner Genome Biology 2011, 12(Suppl 1):P38 (19 September 2011)

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Poster presentation   Open Access

Timing chromosomal abnormalities using mutation data

Steffen Durinck, Christine Ho, Nicholas J Wang, Wilson Liao, Lakshmi R Jakkula, Eric A Collisson, Jennifer Pons, Sai-Wing Chan, Ernest T Lam, Catherine Chu, Kyunghee Park, Sung-woo Hong, Joe S Hur, Nam Huh, Isaac M Neuhaus, Siegrid S Yu, Roy C Grekin, Theodora M Mauro, James E Cleaver, Pui-Yan Kwok, Philip E LeBoit, Gad Getz, Kristian Cibulskis, Jon C Aster, Haiyan Huang, Elizabeth Purdom, Jian Li, Lars Bolund, Sarah T Arron, Joe W Gray, Paul T Spellman, Raymond J Cho et al. Genome Biology 2011, 12(Suppl 1):P39 (19 September 2011)

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Poster presentation   Open Access

RNA-Seq-based transcriptional map of the bovine respiratory disease pathogen Histophilus somni 2336

Ranjit Kumar, Mark L Lawrence, James Watt, Amanda Cooksey, Shane C Burgess, Bindu Nanduri Genome Biology 2011, 12(Suppl 1):P40 (19 September 2011)

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Poster presentation   Open Access

On using optical maps for genome assembly

Henry Lin, Mihai Pop Genome Biology 2011, 12(Suppl 1):P41 (19 September 2011)

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Poster presentation   Open Access

Utilizing whole genome sequences to study population genomics of gene networks: a case study of the Arabidopsis thaliana immune-signaling network

Mridu Middha, Yungil Kim, Peter Morrell, Chad Myers, Fumiaki Katagiri Genome Biology 2011, 12(Suppl 1):P42 (19 September 2011)

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Poster presentation   Open Access

Genomes or exomes: evaluation of cost, time and coverage

Sumit Middha, Jeanne L Theis, Adele H Goodloe, Timothy M Olson, Jean-Pierre A Kocher Genome Biology 2011, 12(Suppl 1):P43 (19 September 2011)

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Poster presentation   Open Access

Integrating whole transcriptome sequence data and public databases for analysis of somatic mutations in tumors

Amin A Momin, Brian P James, Thomas C Motter, Humam N Kadara, Garth Powis, Ignacio I Wistuba Genome Biology 2011, 12(Suppl 1):P44 (19 September 2011)

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Poster presentation   Open Access

Effective detection of rare variants in pooled DNA samples using cross-pool tail-curve analysis

Tejasvi S Niranjan, Abby Adamczyk, Hector Bravo, Margaret A Taub, Sarah J Wheelan, Rafael Irizarry, Tao Wang Genome Biology 2011, 12(Suppl 1):P45 (19 September 2011)

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Poster presentation   Open Access

A comprehensive transcriptomic and biochemical evaluation of a differentiation inducing anti-leukemic principle isolated from Momordica charantia

Punit Prabha, Aparna Dixit Genome Biology 2011, 12(Suppl 1):P46 (19 September 2011)

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Poster presentation   Open Access

Microbial community function and biomarker discovery in the human microbiome

Nicola Segata, Sahar Abubucker, Johannes Goll, Alyxandria M Schubert, Jacques Izard, Brandi L Cantarel, Beltran Rodriguez-Mueller, Levi Waldron, Jeremy Zucker, Mathangi Thiagarajan, Bernard Henrissat, Owen White, Scott T Kelley, Barbara Methé, Patrick D Schloss, Wendy S Garrett, Dirk Gevers, Makedonka Mitreva, Curtis Huttenhower Genome Biology 2011, 12(Suppl 1):P47 (19 September 2011)

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Poster presentation   Open Access

A high-throughput-sequence analysis infrastructure technology investigation framework for the evaluation of next-generation sequencing software

Xiaoyu Liu, Sumit Middha, Steven Hart, Asha Nair, Ahmed Hadad, Patrick Duffy, Jean-Pierre Kocher Genome Biology 2011, 12(Suppl 1):P48 (19 September 2011)

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