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1.
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A simple strategy for heritable chromosomal deletions in zebrafish via the combinatorial action of targeting nucleases
Shimin
Lim,
Yin
Wang,
Xueyao
Yu,
Yian
Huang,
Mark
S
Featherstone,
Karuna
Sampath
Genome Biology 2013, 14:R69 (1 July 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
A method for engineering large-scale deletions enables heritable, specific removal of loci, transcripts or regulatory elements from the zebrafish genome |
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2.
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A CRISPR way to engineer the human genome
Sivaprakash
Ramalingam,
Narayana
Annaluru,
Srinivasan
Chandrasegaran
Genome Biology 2013, 14:107 (26 February 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Srinivasan Chandrasegaran and colleagues explain how recent advances in mammalian genome engineering exploit the natural properties of the bacterial CRISPR system |
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3.
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Synthetic biology: advancing biological frontiers by building synthetic systems
Yvonne
Y
Chen,
Kate
E
Galloway,
Christina
D
Smolke
Genome Biology 2012, 13:240 (20 February 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Christina Smolke and colleagues review an emerging science, whose frontiers include biomanufacturing, radical therapeutic approaches, and insights into natural biological systems
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4.
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Interfacing systems biology and synthetic biology
Allyson
Lister,
Varodom
Charoensawan,
Subhajyoti
De,
Katherine
James,
Sarath Chandra
Janga,
Julian
Huppert
Genome Biology 2009, 10:309 (26 June 2009)
Abstract | Full text | PDF | PubMed
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Editor’s summary
A report of BioSysBio 2009, the IET conference on Synthetic Biology, Systems Biology and Bioinformatics, Cambridge, UK, 23-25 March 2009. |
