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Search microbiome on BioMed Central

#microbiome

25 items(s) found

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1.

Research highlight   Subscription Highly Accessed

Microbiota's 'little helpers': bacteriophages and antibiotic-associated responses in the gut microbiome

Christine L Sun, David A Relman Genome Biology 2013, 14:127 (30 July 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

David Relman and Christine Sun discuss recent research into how bacteriophage mediate the impact of antibiotics on the gut microbiome

2.

Review   Subscription Highly Accessed

The plant microbiome

Thomas R Turner, Euan K James, Philip S Poole Genome Biology 2013, 14:209 (25 June 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Philip Poole and colleagues discuss how genomics approaches are unraveling the complex interactions between plant hosts and microbiome communities

3.

Research   Open Access Highly Accessed

CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes

Quan Zhang, Mina Rho, Haixu Tang, Thomas G Doak, Yuzhen Ye Genome Biology 2013, 14:R40 (29 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Analysis of CRISPR sequences contained in human metagenomic datasets reveals a variety of different targeted mobile genetic elements

4.

Review   Subscription

Studying the microbiology of the indoor environment

Scott T Kelley, Jack A Gilbert Genome Biology 2013, 14:202 (28 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study

5.

Research   Open Access Highly Accessed

Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice

Falk Hildebrand, Thi Loan Anh Nguyen, Brigitta Brinkman, Roberto Yunta, Benedicte Cauwe, Peter Vandenabeele, Adrian Liston, Jeroen Raes Genome Biology 2013, 14:R4 (24 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A new study finds that enterotypes are not only present in mice, but also similar to those in humans

6.

Software   Open Access Highly Accessed

MetAMOS: a modular and open source metagenomic assembly and analysis pipeline

Todd J Treangen, Sergey Koren, Daniel D Sommer, Bo Liu, Irina Astrovskaya, Brian Ondov, Aaron E Darling, Adam M Phillippy, Mihai Pop Genome Biology 2013, 14:R2 (15 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A modular, metagenomic analysis and assembly pipeline that inputs next-generation sequencing reads to generate genomic scaffolds and open reading frames

7.

Research   Open Access Highly Accessed

Biogeography of the ecosystems of the healthy human body

Yanjiao Zhou, Hongyu Gao, Kathie A Mihindukulasuriya, Patricio S La Rosa, Kristine M Wylie, Tatiana Vishnivetskaya, Mircea Podar, Barb Warner, Phillip I Tarr, David E Nelson, J Fortenberry, Martin J Holland, Sarah E Burr, William D Shannon, Erica Sodergren, George M Weinstock Genome Biology 2013, 14:R1 (14 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

As part of the Human Microbiome Project, taxonomic analyses were performed on the bacteria from 22 body sites on 279 subjects

8.

Research   Open Access

Phylogeographic variation in recombination rates within a global clone of methicillin-resistant Staphylococcus aureus

Santiago Castillo-Ramírez, Jukka Corander, Pekka Marttinen, Mona Aldeljawi, William P Hanage, Henrik Westh, Kit Boye, Zeynep Gulay, Stephen D Bentley, Julian Parkhill, Matthew T Holden, Edward J Feil Genome Biology 2012, 13:R126 (27 December 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Different evolution rates of methicillin-resistant Staphylococcus aureus clone ST239 collected in different geographical locations are caused by fast global dissemination

9.

Method   Open Access Highly Accessed

Ray Meta: scalable de novo metagenome assembly and profiling

Sébastien Boisvert, Frédéric Raymond, Élénie Godzaridis, François Laviolette, Jacques Corbeil Genome Biology 2012, 13:R122 (22 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A scalable, de novo metagenomic assembly method that couples taxonomic and ontology profiling

10.

Research   Open Access

Microevolutionary analysis of Clostridium difficile genomes to investigate transmission

Xavier Didelot, David W Eyre, Madeleine Cule, Camilla LC Ip, M Ansari, David Griffiths, Alison Vaughan, Lily O'Connor, Tanya Golubchik, Elizabeth M Batty, Paolo Piazza, Daniel J Wilson, Rory Bowden, Peter J Donnelly, Kate E Dingle, Mark Wilcox, A Walker, Derrick W Crook, Tim E A Peto, Rosalind M Harding Genome Biology 2012, 13:R118 (21 December 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology |  Editor’s summary

Transmission events of Clostridium difficile are inferred from whole-genome sequencing of isolates and estimating divergence time of bacterial strains

11.

Research   Open Access Highly Accessed

Microbiome dynamics of human epidermis following skin barrier disruption

Patrick LJM Zeeuwen, Jos Boekhorst, Ellen H van den Bogaard, Heleen D de Koning, Peter MC van de Kerkhof, Delphine M Saulnier, Iris I van Swam, Sacha AFT van Hijum, Michiel Kleerebezem, Joost Schalkwijk, Harro M Timmerman Genome Biology 2012, 13:R101 (15 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

An analysis of the microbiota of the surface and deeper layers of skin, and how it changes following skin barrier disruption

12.

Research highlight   Subscription

Functional predictions from inference and observation in sequence-based inflammatory bowel disease research

Folker Meyer, William L Trimble, Eugene B Chang, Kim M Handley Genome Biology 2012, 13:169 (26 September 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Research Highlight: important advances in understanding the gut microbiome composition and microbial metabolism in patients with IBD

13.

Research   Open Access Highly Accessed

Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment

Xochitl C Morgan, Timothy L Tickle, Harry Sokol, Dirk Gevers, Kathryn L Devaney, Doyle V Ward, Joshua A Reyes, Samir A Shah, Neal LeLeiko, Scott B Snapper, Athos Bousvaros, Joshua Korzenik, Bruce E Sands, Ramnik J Xavier, Curtis Huttenhower Genome Biology 2012, 13:R79 (26 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

An analysis of the microbes and microbial metabolism present in intestinal biopsies and stool samples from 231 IBD and healthy subjects

14.

Research   Open Access Highly Accessed

Staphylococcus epidermidis pan-genome sequence analysis reveals diversity of skin commensal and hospital infection-associated isolates

Sean Conlan, Lilia A Mijares, Jesse Becker, Robert W Blakesley, Gerard G Bouffard, Shelise Brooks, Holly Coleman, Jyoti Gupta, Natalie Gurson, Morgan Park, Brian Schmidt, Pamela J Thomas, Michael Otto, Heidi H Kong, Patrick R Murray, Julia A Segre Genome Biology 2012, 13:R64 (25 July 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Comparative genomics of skin commensal and hospital infection-associated isolates uncovers a putative clinical biomarker

15.

Method   Open Access

A tool kit for quantifying eukaryotic rRNA gene sequences from human microbiome samples

Serena Dollive, Gregory L Peterfreund, Scott Sherrill-Mix, Kyle Bittinger, Rohini Sinha, Christian Hoffmann, Christopher S Nabel, David A Hill, David Artis, Michael A Bachman, Rebecca Custers-Allen, Stephanie Grunberg, Gary D Wu, James D Lewis, Frederic D Bushman Genome Biology 2012, 13:R60 (3 July 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

BROCC, a pipeline for the analysis of eukaryotes of microbiomes using conserved ribosomal rDNA sequences as markers

16.

Research   Open Access Highly Accessed

Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples

Nicola Segata, Susan Haake, Peter Mannon, Katherine P Lemon, Levi Waldron, Dirk Gevers, Curtis Huttenhower, Jacques Izard Genome Biology 2012, 13:R42 (14 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The Human Microbiome Project's analysis of ten sites in the digestive tract of healthy human adults

17.

Research highlight   Free Highly Accessed

We are what we eat: how the diet of infants affects their gut microbiome

Mihai Pop Genome Biology 2012, 13:152 (30 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

We are what we eat: Mihai Pop highlights our Research article investigating the impact of diet on an infant's gut

18.

Research   Open Access Highly Accessed

A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response

Scott Schwartz, Iddo Friedberg, Ivan V Ivanov, Laurie A Davidson, Jennifer S Goldsby, David B Dahl, Damir Herman, Mei Wang, Sharon M Donovan, Robert S Chapkin Genome Biology 2012, 13:r32 (30 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A novel host-microbiome analysis method reveals a transcriptional immune response in the breast-fed infant gut associated with diet-specific microbiota

19.

Method   Open Access Highly Accessed

Efficient and robust RNA-seq process for cultured bacteria and complex community transcriptomes

Georgia Giannoukos, Dawn M Ciulla, Katherine Huang, Brian J Haas, Jacques Izard, Joshua Z Levin, Jonathan Livny, Ashlee M Earl, Dirk Gevers, Doyle V Ward, Chad Nusbaum, Bruce W Birren, Andreas Gnirke Genome Biology 2012, 13:r23 (28 March 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A method is presented for transcriptome sequencing of complex bacterial mixtures or communities

20.

Method   Open Access Highly Accessed

Metagenomic biomarker discovery and explanation

Nicola Segata, Jacques Izard, Levi Waldron, Dirk Gevers, Larisa Miropolsky, Wendy S Garrett, Curtis Huttenhower Genome Biology 2011, 12:R60 (24 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A method for distinguishing microbial populations from metagenomic data is presented

21.

Research highlight   Free Highly Accessed

The volatile microbiome

George M Weinstock Genome Biology 2011, 12:114 (30 May 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

George Weinstock highlights Genome Biology's latest research article on human microbiota

22.

Research   Open Access Highly Accessed

Moving pictures of the human microbiome

J Gregory Caporaso, Christian L Lauber, Elizabeth K Costello, Donna Berg-Lyons, Antonio Gonzalez, Jesse Stombaugh, Dan Knights, Pawel Gajer, Jacques Ravel, Noah Fierer, Jeffrey I Gordon, Rob Knight Genome Biology 2011, 12:R50 (30 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

The dynamism of microbiome populations is seen in daily samples from a landmark multi-body site, multi-individual study

23.

Method   Open Access Highly Accessed

EMIRGE: reconstruction of full-length ribosomal genes from microbial community short read sequencing data

Christopher S Miller, Brett J Baker, Brian C Thomas, Steven W Singer, Jillian F Banfield Genome Biology 2011, 12:R44 (19 May 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Reconstructing full length rRNA sequences from short reads to estimate microbial community structure

24.

Review   Free Highly Accessed

Direct sequencing of the human microbiome readily reveals community differences

Justin Kuczynski, Elizabeth K Costello, Diana R Nemergut, Jesse Zaneveld, Christian L Lauber, Dan Knights, Omry Koren, Noah Fierer, Scott T Kelley, Ruth E Ley, Jeffrey I Gordon, Rob Knight Genome Biology 2010, 11:210 (5 May 2010)

This article is part of a collection on 10th Anniversary...

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Future sequencing of the human microbiota will require greater breadth rather than depth.

25.

Research   Open Access Highly Accessed

Community-wide analysis of microbial genome sequence signatures

Gregory J Dick, Anders F Andersson, Brett J Baker, Sheri L Simmons, Brian C Thomas, A Pepper Yelton, Jillian F Banfield Genome Biology 2009, 10:R85 (21 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Genome signatures are used to identify and cluster sequences de novo from an acid biofilm microbial community metagenomic dataset, revealing information about the low-abundance community members.

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