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1.
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Microbiota's 'little helpers': bacteriophages and antibiotic-associated responses in the gut microbiome
Christine
L
Sun,
David
A
Relman
Genome Biology 2013, 14:127 (30 July 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
David Relman and Christine Sun discuss recent research into how bacteriophage mediate the impact of antibiotics on the gut microbiome
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2.
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The plant microbiome
Thomas
R
Turner,
Euan
K
James,
Philip
S
Poole
Genome Biology 2013, 14:209 (25 June 2013)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Philip Poole and colleagues discuss how genomics approaches are unraveling the complex interactions between plant hosts and microbiome communities
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3.
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CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes
Quan
Zhang,
Mina
Rho,
Haixu
Tang,
Thomas
G
Doak,
Yuzhen
Ye
Genome Biology 2013, 14:R40 (29 April 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Analysis of CRISPR sequences contained in human metagenomic datasets reveals a variety of different targeted mobile genetic elements
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4.
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Studying the microbiology of the indoor environment
Scott
T
Kelley,
Jack
A
Gilbert
Genome Biology 2013, 14:202 (28 February 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study
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5.
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Inflammation-associated enterotypes, host genotype, cage and inter-individual effects drive gut microbiota variation in common laboratory mice
Falk
Hildebrand,
Thi Loan Anh
Nguyen,
Brigitta
Brinkman,
Roberto
Yunta,
Benedicte
Cauwe,
Peter
Vandenabeele,
Adrian
Liston,
Jeroen
Raes
Genome Biology 2013, 14:R4 (24 January 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
A new study finds that enterotypes are not only present in mice, but also similar to those in humans
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6.
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MetAMOS: a modular and open source metagenomic assembly and analysis pipeline
Todd
J
Treangen,
Sergey
Koren,
Daniel
D
Sommer,
Bo
Liu,
Irina
Astrovskaya,
Brian
Ondov,
Aaron
E
Darling,
Adam
M
Phillippy,
Mihai
Pop
Genome Biology 2013, 14:R2 (15 January 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
A modular, metagenomic analysis and assembly pipeline that inputs next-generation sequencing reads to generate genomic scaffolds and open reading frames
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7.
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Biogeography of the ecosystems of the healthy human body
Yanjiao
Zhou,
Hongyu
Gao,
Kathie
A
Mihindukulasuriya,
Patricio
S
La Rosa,
Kristine
M
Wylie,
Tatiana
Vishnivetskaya,
Mircea
Podar,
Barb
Warner,
Phillip
I
Tarr,
David
E
Nelson,
J
Fortenberry,
Martin
J
Holland,
Sarah
E
Burr,
William
D
Shannon,
Erica
Sodergren,
George
M
Weinstock
Genome Biology 2013, 14:R1 (14 January 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
As part of the Human Microbiome Project, taxonomic analyses were performed on the bacteria from 22 body sites on 279 subjects
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8.
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Phylogeographic variation in recombination rates within a global clone of methicillin-resistant Staphylococcus aureus
Santiago
Castillo-Ramírez,
Jukka
Corander,
Pekka
Marttinen,
Mona
Aldeljawi,
William
P
Hanage,
Henrik
Westh,
Kit
Boye,
Zeynep
Gulay,
Stephen
D
Bentley,
Julian
Parkhill,
Matthew
T
Holden,
Edward
J
Feil
Genome Biology 2012, 13:R126 (27 December 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Different evolution rates of methicillin-resistant Staphylococcus aureus clone ST239 collected in different geographical locations are caused by fast global dissemination
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9.
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Ray Meta: scalable de novo metagenome assembly and profiling
Sébastien
Boisvert,
Frédéric
Raymond,
Élénie
Godzaridis,
François
Laviolette,
Jacques
Corbeil
Genome Biology 2012, 13:R122 (22 December 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
A scalable, de novo metagenomic assembly method that couples taxonomic and ontology profiling
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10.
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Microevolutionary analysis of Clostridium difficile genomes to investigate transmission
Xavier
Didelot,
David
W
Eyre,
Madeleine
Cule,
Camilla
LC
Ip,
M
Ansari,
David
Griffiths,
Alison
Vaughan,
Lily
O'Connor,
Tanya
Golubchik,
Elizabeth
M
Batty,
Paolo
Piazza,
Daniel
J
Wilson,
Rory
Bowden,
Peter
J
Donnelly,
Kate
E
Dingle,
Mark
Wilcox,
A
Walker,
Derrick
W
Crook,
Tim
E
A Peto,
Rosalind
M
Harding
Genome Biology 2012, 13:R118 (21 December 2012)
Abstract | Full text | PDF | PubMed | F1000 Biology
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Editor’s summary
Transmission events of Clostridium difficile are inferred from whole-genome sequencing of isolates and estimating divergence time of bacterial strains
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11.
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Microbiome dynamics of human epidermis following skin barrier disruption
Patrick
LJM
Zeeuwen,
Jos
Boekhorst,
Ellen
H
van den Bogaard,
Heleen
D
de Koning,
Peter
MC
van de Kerkhof,
Delphine
M
Saulnier,
Iris
I
van Swam,
Sacha
AFT
van Hijum,
Michiel
Kleerebezem,
Joost
Schalkwijk,
Harro
M
Timmerman
Genome Biology 2012, 13:R101 (15 November 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
An analysis of the microbiota of the surface and deeper layers of skin, and how it changes following skin barrier disruption
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12.
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Functional predictions from inference and observation in sequence-based inflammatory bowel disease research
Folker
Meyer,
William
L
Trimble,
Eugene
B
Chang,
Kim
M
Handley
Genome Biology 2012, 13:169 (26 September 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Research Highlight: important advances in understanding the gut microbiome composition and microbial metabolism in patients with IBD
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13.
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Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment
Xochitl
C
Morgan,
Timothy
L
Tickle,
Harry
Sokol,
Dirk
Gevers,
Kathryn
L
Devaney,
Doyle
V
Ward,
Joshua
A
Reyes,
Samir
A
Shah,
Neal
LeLeiko,
Scott
B
Snapper,
Athos
Bousvaros,
Joshua
Korzenik,
Bruce
E
Sands,
Ramnik
J
Xavier,
Curtis
Huttenhower
Genome Biology 2012, 13:R79 (26 September 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
An analysis of the microbes and microbial metabolism present in intestinal biopsies and stool samples from 231 IBD and healthy subjects
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14.
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Staphylococcus epidermidis pan-genome sequence analysis reveals diversity of skin commensal and hospital infection-associated isolates
Sean
Conlan,
Lilia
A
Mijares,
Jesse
Becker,
Robert
W
Blakesley,
Gerard
G
Bouffard,
Shelise
Brooks,
Holly
Coleman,
Jyoti
Gupta,
Natalie
Gurson,
Morgan
Park,
Brian
Schmidt,
Pamela
J
Thomas,
Michael
Otto,
Heidi
H
Kong,
Patrick
R
Murray,
Julia
A
Segre
Genome Biology 2012, 13:R64 (25 July 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Comparative genomics of skin commensal and hospital infection-associated isolates uncovers a putative clinical biomarker
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15.
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A tool kit for quantifying eukaryotic rRNA gene sequences from human microbiome samples
Serena
Dollive,
Gregory
L
Peterfreund,
Scott
Sherrill-Mix,
Kyle
Bittinger,
Rohini
Sinha,
Christian
Hoffmann,
Christopher
S
Nabel,
David
A
Hill,
David
Artis,
Michael
A
Bachman,
Rebecca
Custers-Allen,
Stephanie
Grunberg,
Gary
D
Wu,
James
D
Lewis,
Frederic
D
Bushman
Genome Biology 2012, 13:R60 (3 July 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
BROCC, a pipeline for the analysis of eukaryotes of microbiomes using conserved ribosomal rDNA sequences as markers
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16.
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Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples
Nicola
Segata,
Susan
Haake,
Peter
Mannon,
Katherine
P
Lemon,
Levi
Waldron,
Dirk
Gevers,
Curtis
Huttenhower,
Jacques
Izard
Genome Biology 2012, 13:R42 (14 June 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
The Human Microbiome Project's analysis of ten sites in the digestive tract of healthy human adults
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17.
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We are what we eat: how the diet of infants affects their gut microbiome
Mihai
Pop
Genome Biology 2012, 13:152 (30 April 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
We are what we eat: Mihai Pop highlights our Research article investigating the impact of diet on an infant's gut
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18.
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A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response
Scott
Schwartz,
Iddo
Friedberg,
Ivan
V
Ivanov,
Laurie
A
Davidson,
Jennifer
S
Goldsby,
David
B
Dahl,
Damir
Herman,
Mei
Wang,
Sharon
M
Donovan,
Robert
S
Chapkin
Genome Biology 2012, 13:r32 (30 April 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
A novel host-microbiome analysis method reveals a transcriptional immune response in the breast-fed infant gut associated with diet-specific microbiota
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19.
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Efficient and robust RNA-seq process for cultured bacteria and complex community transcriptomes
Georgia
Giannoukos,
Dawn
M
Ciulla,
Katherine
Huang,
Brian
J
Haas,
Jacques
Izard,
Joshua
Z
Levin,
Jonathan
Livny,
Ashlee
M
Earl,
Dirk
Gevers,
Doyle
V
Ward,
Chad
Nusbaum,
Bruce
W
Birren,
Andreas
Gnirke
Genome Biology 2012, 13:r23 (28 March 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
A method is presented for transcriptome sequencing of complex bacterial mixtures or communities
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20.
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Metagenomic biomarker discovery and explanation
Nicola
Segata,
Jacques
Izard,
Levi
Waldron,
Dirk
Gevers,
Larisa
Miropolsky,
Wendy
S
Garrett,
Curtis
Huttenhower
Genome Biology 2011, 12:R60 (24 June 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
A method for distinguishing microbial populations from metagenomic data is presented
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21.
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The volatile microbiome
George
M
Weinstock
Genome Biology 2011, 12:114 (30 May 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
George Weinstock highlights Genome Biology's latest research article on human microbiota
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22.
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Moving pictures of the human microbiome
J Gregory
Caporaso,
Christian
L
Lauber,
Elizabeth
K
Costello,
Donna
Berg-Lyons,
Antonio
Gonzalez,
Jesse
Stombaugh,
Dan
Knights,
Pawel
Gajer,
Jacques
Ravel,
Noah
Fierer,
Jeffrey
I
Gordon,
Rob
Knight
Genome Biology 2011, 12:R50 (30 May 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology
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Editor’s summary
The dynamism of microbiome populations is seen in daily samples from a landmark multi-body site, multi-individual study
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23.
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EMIRGE: reconstruction of full-length ribosomal genes from microbial community short read sequencing data
Christopher
S
Miller,
Brett
J
Baker,
Brian
C
Thomas,
Steven
W
Singer,
Jillian
F
Banfield
Genome Biology 2011, 12:R44 (19 May 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Reconstructing full length rRNA sequences from short reads to estimate microbial community structure
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24.
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Direct sequencing of the human microbiome readily reveals community differences
Justin
Kuczynski,
Elizabeth
K
Costello,
Diana
R
Nemergut,
Jesse
Zaneveld,
Christian
L
Lauber,
Dan
Knights,
Omry
Koren,
Noah
Fierer,
Scott
T
Kelley,
Ruth
E
Ley,
Jeffrey
I
Gordon,
Rob
Knight
Genome Biology 2010, 11:210 (5 May 2010)
This article is part of a collection on
10th Anniversary...
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Future sequencing of the human microbiota will require greater breadth rather than depth.
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25.
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Community-wide analysis of microbial genome sequence signatures
Gregory
J
Dick,
Anders
F
Andersson,
Brett
J
Baker,
Sheri
L
Simmons,
Brian
C
Thomas,
A Pepper
Yelton,
Jillian
F
Banfield
Genome Biology 2009, 10:R85 (21 August 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Genome signatures are used to identify and cluster sequences de novo from an acid biofilm microbial community metagenomic dataset, revealing information about the low-abundance community members.
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