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1.
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CRISPR-Cas systems target a diverse collection of invasive mobile genetic elements in human microbiomes
Quan
Zhang,
Mina
Rho,
Haixu
Tang,
Thomas
G.
Doak,
Yuzhen
Ye
Genome Biology 2013, 14:R40 (29 April 2013)
Abstract | Provisional PDF
| PubMed
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Editor’s summary
Analysis of CRISPR sequences contained in human metagenomic datasets reveals a variety of different targeted mobile genetic elements
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2.
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Studying the microbiology of the indoor environment
Scott
T
Kelley,
Jack
A
Gilbert
Genome Biology 2013, 14:202 (28 February 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Scott Kelley and Jack Gilbert review the microbiology of the built environment, and highlight how genomics can empower its study
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3.
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Biogeography of the ecosystems of the healthy human body
Yanjiao
Zhou,
Hongyu
Gao,
Kathie
A
Mihindukulasuriya,
Patricio
S LA
Rosa,
Kristine
M
Wylie,
Tatiana
Vishnivetskaya,
Mircea
Podar,
Barb
Warner,
Phillip
I
Tarr,
David
E
Nelson,
J Dennis
Fortenberry,
Martin
J
Holland,
Sarah
E
Burr,
William
D
Shannon,
Erica
Sodergren,
George
M
Weinstock
Genome Biology 2013, 14:R1 (14 January 2013)
Abstract | Provisional PDF
| PubMed
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Editor’s summary
As part of the Human Microbiome Project, taxonomic analyses were performed on the bacteria from 22 body sites on 279 subjects
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4.
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Phylogeographic variation in recombination rates within a global clone of methicillin-resistant Staphylococcus aureus
Santiago
Castillo-Ramírez,
Jukka
Corander,
Pekka
Marttinen,
Mona
Aldeljawi,
William
P
Hanage,
Henrik
Westh,
Kit
Boye,
Zeynep
Gulay,
Stephen
D
Bentley,
Julian
Parkhill,
Matthew
T
Holden,
Edward
J
Feil
Genome Biology 2012, 13:R126 (27 December 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Different evolution rates of methicillin-resistant Staphylococcus aureus clone ST239 collected in different geographical locations are caused by fast global dissemination
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5.
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Ray Meta: scalable de novo metagenome assembly and profiling
Sébastien
Boisvert,
Frédéric
Raymond,
Élénie
Godzaridis,
François
Laviolette,
Jacques
Corbeil
Genome Biology 2012, 13:R122 (22 December 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
A scalable, de novo metagenomic assembly method that couples taxonomic and ontology profiling
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6.
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Microevolutionary analysis of Clostridium difficile genomes to investigate transmission
Xavier
Didelot,
David
W
Eyre,
Madeleine
Cule,
Camilla
LC
Ip,
M
Ansari,
David
Griffiths,
Alison
Vaughan,
Lily
O'Connor,
Tanya
Golubchik,
Elizabeth
M
Batty,
Paolo
Piazza,
Daniel
J
Wilson,
Rory
Bowden,
Peter
J
Donnelly,
Kate
E
Dingle,
Mark
Wilcox,
A
Walker,
Derrick
W
Crook,
Tim
E
A Peto,
Rosalind
M
Harding
Genome Biology 2012, 13:R118 (21 December 2012)
Abstract | Full text | PDF | PubMed | F1000 Biology
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Editor’s summary
Transmission events of Clostridium difficile are inferred from whole-genome sequencing of isolates and estimating divergence time of bacterial strains
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7.
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Microbiome dynamics of human epidermis following skin barrier disruption
Patrick
LJM
Zeeuwen,
Jos
Boekhorst,
Ellen
H
van den Bogaard,
Heleen
D
de Koning,
Peter
MC
van de Kerkhof,
Delphine
M
Saulnier,
Iris
I
van Swam,
Sacha
AFT
van Hijum,
Michiel
Kleerebezem,
Joost
Schalkwijk,
Harro
M
Timmerman
Genome Biology 2012, 13:R101 (15 November 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
An analysis of the microbiota of the surface and deeper layers of skin, and how it changes following skin barrier disruption
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8.
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Functional predictions from inference and observation in sequence-based inflammatory bowel disease research
Folker
Meyer,
William
L
Trimble,
Eugene
B
Chang,
Kim
M
Handley
Genome Biology 2012, 13:169 (26 September 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Research Highlight: important advances in understanding the gut microbiome composition and microbial metabolism in patients with IBD
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9.
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Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment
Xochitl
C
Morgan,
Timothy
L
Tickle,
Harry
Sokol,
Dirk
Gevers,
Kathryn
L
Devaney,
Doyle
V
Ward,
Joshua
A
Reyes,
Samir
A
Shah,
Neal
LeLeiko,
Scott
B
Snapper,
Athos
Bousvaros,
Joshua
Korzenik,
Bruce
E
Sands,
Ramnik
J
Xavier,
Curtis
Huttenhower
Genome Biology 2012, 13:R79 (26 September 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
An analysis of the microbes and microbial metabolism present in intestinal biopsies and stool samples from 231 IBD and healthy subjects
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10.
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Staphylococcus epidermidis pan-genome sequence analysis reveals diversity of skin commensal and hospital infection-associated isolates
Sean
Conlan,
Lilia
A
Mijares,
Jesse
Becker,
Robert
W
Blakesley,
Gerard
G
Bouffard,
Shelise
Brooks,
Holly
Coleman,
Jyoti
Gupta,
Natalie
Gurson,
Morgan
Park,
Brian
Schmidt,
Pamela
J
Thomas,
Michael
Otto,
Heidi
H
Kong,
Patrick
R
Murray,
Julia
A
Segre
Genome Biology 2012, 13:R64 (25 July 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Comparative genomics of skin commensal and hospital infection-associated isolates uncovers a putative clinical biomarker
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11.
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A tool kit for quantifying eukaryotic rRNA gene sequences from human microbiome samples
Serena
Dollive,
Gregory
L
Peterfreund,
Scott
Sherrill-Mix,
Kyle
Bittinger,
Rohini
Sinha,
Christian
Hoffmann,
Christopher
S
Nabel,
David
A
Hill,
David
Artis,
Michael
A
Bachman,
Rebecca
Custers-Allen,
Stephanie
Grunberg,
Gary
D
Wu,
James
D
Lewis,
Frederic
D
Bushman
Genome Biology 2012, 13:R60 (3 July 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
BROCC, a pipeline for the analysis of eukaryotes of microbiomes using conserved ribosomal rDNA sequences as markers
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12.
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Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples
Nicola
Segata,
Susan
Haake,
Peter
Mannon,
Katherine
P
Lemon,
Levi
Waldron,
Dirk
Gevers,
Curtis
Huttenhower,
Jacques
Izard
Genome Biology 2012, 13:R42 (14 June 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
The Human Microbiome Project's analysis of ten sites in the digestive tract of healthy human adults
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13.
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We are what we eat: how the diet of infants affects their gut microbiome
Mihai
Pop
Genome Biology 2012, 13:152 (30 April 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
We are what we eat: Mihai Pop highlights our Research article investigating the impact of diet on an infant's gut
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14.
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A metagenomic study of diet-dependent interaction between gut microbiota and host in infants reveals differences in immune response
Scott
Schwartz,
Iddo
Friedberg,
Ivan
V
Ivanov,
Laurie
A
Davidson,
Jennifer
S
Goldsby,
David
B
Dahl,
Damir
Herman,
Mei
Wang,
Sharon
M
Donovan,
Robert
S
Chapkin
Genome Biology 2012, 13:r32 (30 April 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
A novel host-microbiome analysis method reveals a transcriptional immune response in the breast-fed infant gut associated with diet-specific microbiota
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15.
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Efficient and robust RNA-seq process for cultured bacteria and complex community transcriptomes
Georgia
Giannoukos,
Dawn
M
Ciulla,
Katherine
Huang,
Brian
J
Haas,
Jacques
Izard,
Joshua
Z
Levin,
Jonathan
Livny,
Ashlee
M
Earl,
Dirk
Gevers,
Doyle
V
Ward,
Chad
Nusbaum,
Bruce
W
Birren,
Andreas
Gnirke
Genome Biology 2012, 13:r23 (28 March 2012)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
A method is presented for transcriptome sequencing of complex bacterial mixtures or communities
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16.
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Metagenomic biomarker discovery and explanation
Nicola
Segata,
Jacques
Izard,
Levi
Waldron,
Dirk
Gevers,
Larisa
Miropolsky,
Wendy
S
Garrett,
Curtis
Huttenhower
Genome Biology 2011, 12:R60 (24 June 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
A method for distinguishing microbial populations from metagenomic data is presented
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17.
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The volatile microbiome
George
M
Weinstock
Genome Biology 2011, 12:114 (30 May 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
George Weinstock highlights Genome Biology's latest research article on human microbiota
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18.
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Moving pictures of the human microbiome
J Gregory
Caporaso,
Christian
L
Lauber,
Elizabeth
K
Costello,
Donna
Berg-Lyons,
Antonio
Gonzalez,
Jesse
Stombaugh,
Dan
Knights,
Pawel
Gajer,
Jacques
Ravel,
Noah
Fierer,
Jeffrey
I
Gordon,
Rob
Knight
Genome Biology 2011, 12:R50 (30 May 2011)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology
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Editor’s summary
The dynamism of microbiome populations is seen in daily samples from a landmark multi-body site, multi-individual study
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19.
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EMIRGE: reconstruction of full-length ribosomal genes from microbial community short read sequencing data
Christopher
S
Miller,
Brett
J
Baker,
Brian
C
Thomas,
Steven
W
Singer,
Jillian
F
Banfield
Genome Biology 2011, 12:R44 (19 May 2011)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Reconstructing full length rRNA sequences from short reads to estimate microbial community structure
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20.
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Direct sequencing of the human microbiome readily reveals community differences
Justin
Kuczynski,
Elizabeth
K
Costello,
Diana
R
Nemergut,
Jesse
Zaneveld,
Christian
L
Lauber,
Dan
Knights,
Omry
Koren,
Noah
Fierer,
Scott
T
Kelley,
Ruth
E
Ley,
Jeffrey
I
Gordon,
Rob
Knight
Genome Biology 2010, 11:210 (5 May 2010)
This article is part of a collection on
10th Anniversary...
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Future sequencing of the human microbiota will require greater breadth rather than depth.
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21.
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Community-wide analysis of microbial genome sequence signatures
Gregory
J
Dick,
Anders
F
Andersson,
Brett
J
Baker,
Sheri
L
Simmons,
Brian
C
Thomas,
A Pepper
Yelton,
Jillian
F
Banfield
Genome Biology 2009, 10:R85 (21 August 2009)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Genome signatures are used to identify and cluster sequences de novo from an acid biofilm microbial community metagenomic dataset, revealing information about the low-abundance community members.
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