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1.
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Adult monozygotic twins discordant for intra-uterine growth have indistinguishable genome-wide DNA methylation profiles
Nicole
YP
Souren,
Pavlo
Lutsik,
Gilles
Gasparoni,
Sascha
Tierling,
Jasmin
Gries,
Matthias
Riemenschneider,
Jean-Pierre
Fryns,
Catherine
Derom,
Maurice
P
Zeegers,
Jörn
Walter
Genome Biology 2013, 14:R44 (26 May 2013)
Abstract | Full text | PDF | PubMed | F1000 Biology
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Editor’s summary
Monozygotic twins discordant for birth weight have very similar DNA methylation profiles |
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2.
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Inactive or moderately active human promoters are enriched for inter-individual epialleles
Carolina
Gemma,
Sreeram
V
Ramagopalan,
Thomas
A
Down,
Huriya
Beyan,
Mohammed
I
Hawa,
Michelle
L
Holland,
Paul
J
Hurd,
Gavin
Giovannoni,
R
David Leslie,
George
C
Ebers,
Vardhman
K
Rakyan
Genome Biology 2013, 14:R43 (25 May 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Epialleles between monozygotic twins are temporally stable, associated with chromatin changes and enriched in transcriptionally inactive regions |
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3.
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Longitudinal, genome-scale analysis of DNA methylation in twins from birth to 18 months of age reveals rapid epigenetic change in early life and pair-specific effects of discordance
David
Martino,
Yuk
Loke,
Lavinia
Gordon,
Miina
Ollikainen,
Mark
N
Cruickshank,
Richard
Saffery,
Jeffrey
M
Craig
Genome Biology 2013, 14:R42 (22 May 2013)
Abstract | Full text | PDF | PubMed
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Editor’s summary
A longitudinal study of DNA methylation in twins at birth and 18 months finds that some loci drift in methylation status |
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4.
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DNA methylation studies using twins: what are they telling us?
Jordana
T
Bell,
Tim
D
Spector
Genome Biology 2012, 13:172 (18 October 2012)
Abstract | Full text | PDF | PubMed
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Editor’s summary
Jordana Bell and Tim Spector on what twin studies can teach us about human epigenetics
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