Genome Biology aims to provide review material that readers need in order to assess and evaluate progress in genomic and post-genomic research. Tutorials provide 'beginner's guides' to particular tools and resources, aiming to address the questions non-specialists most often want answered. Tutorials are usually commissioned, with the editors aiming to ensure coverage of all relevant areas of biology and genomics but suggestions of tutorials are welcome.

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(20 December 2004)

This article describes the steps involved and the considerations needed for successful granting of a patent for biological ideas and technologies.

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(19 December 2001)

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(27 September 2001)

Searching for similarities between biological sequences is the principal means by which bioinformatics contributes to our understanding of biology. Of the various informatics tools developed to accomplish this task, the most widely used is BLAST, the basic local alignment search tool. This article discusses the principles, workings, applications and potential pitfalls of BLAST, focusing on the implementation developed at the National Center for Biotechnology Information.

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(5 June 2001)

The volume of human genome sequence and the variety of web-based tools to access it continue to grow at an impressive rate, but a working knowledge of certain key resources can be sufficient to get the most from your genome. This article provides an update to Genome Biology 2000, 1(4):reviews2001.1-2001.5.

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(16 October 2000)

Much is expected of the draft human genome sequence, and yet there is no central resource to host the plethora of sequence and mapping information available. Consequently, finding the most useful and reliable human genome data and resources currently available on the web can be challenging, but is not impossible.